Developmental Biology

Download e-book for iPad: Adherens Junctions: from Molecular Mechanisms to Tissue by Tony Harris

By Tony Harris

ISBN-10: 9400741855

ISBN-13: 9789400741850

ISBN-10: 9400796161

ISBN-13: 9789400796164

Cell–cell adhesion is prime for the advance and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the simplest understood cell-cell adhesion complexes. during this quantity, a gaggle of across the world famous specialists reports AJ biology over a variety of association; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and total animal improvement. AJs have additionally been a vital part of animal evolution, and play critical roles in melanoma improvement, pathogen an infection and different ailments. This publication addresses significant questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins engage to gather AJs and mediate adhesion?
• How do AJs interface with different mobile equipment to couple adhesion with the total mobile?
• How do AJs have an effect on phone behaviour and multicellular improvement?
• How can irregular AJ task result in disease?

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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease: 60 (Subcellular Biochemistry) by Tony Harris


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